Sermorelin is a synthetic version of a naturally occurring substance that causes release of growth hormones from the pituitary gland. Growth hormones are naturally produced by the pituitary gland and are necessary for growth in children. 

Is sermorelin used for weight loss?

Sermorelin is also known to potentially help patients lose weight because HGH increases the production of insulin-like Growth Factor-1 (IGF-1). Higher levels of IGF-1 result in higher levels of metabolism therefore aiding in weight loss. 

Does sermorelin make you look younger? 

Sermorelin causes an increase in growth hormone and cell turnover, and this naturally improves the quality of your skin. Most patients see a reduction in wrinkles and fine lines, and overall tighter skin, and possibly longer eye lashes. 

There is not a lot of research on the effects of growth hormone secretagogues on skin texture and thickness because most growth hormone research has focused on changes in body composition. Stimulating natural growth hormone release is expected to increase collagen production and skin cell growth. Since growth hormone is an anabolic hormone, it increases skin cell size, growth, and cellular differentiation. Growth hormone stimulates the release of growth factors that can increase collagen production, skin density, mechanical strength, and skin thickness. Sermorelin is expected to help your skin maintain a more youthful appearance.  Sermorelin can also help skin repair post-injury or after surgery. 

Is sermorelin a steroid?

Sermorelin is not a steroid or growth hormone. It's a bio-identical substance that stimulates the pituitary gland to make more growth hormone, which is basically a man-made version of the naturally occurring substance responsible for releasing growth hormone.

Does sermorelin burn fat?

Sermorelin therapy can reduce body fat by 5-8% over the course of a year. It works by stimulating the pituitary gland to release human growth hormone, which either binds to growth hormone receptors or is carried out by insulin growth factor 1 (IGF-1). Higher IGF-1 levels lead to increased muscle mass and bone density, plus less fat. 

Aging may lower natural growth hormone levels, so sermorelin helps restore them.

Vitamin B12 (cobalamin) is an essential, water-soluble nutrient critical for red blood cell production, neurological function, DNA synthesis, and cellular metabolism. The injectable form—especially methylcobalamin—delivers B12 directly into your bloodstream or subcutaneous tissue for optimal absorption, bypassing the gut. This is particularly important since B12 absorption naturally declines with age, GI disorders, or certain medications. B12 is crucial for anyone focused on energy, cognition, and aging well.

Nicotinamide Adenine Dinucleotide is a form of Vitamin B3 (Niacin). This is an essential coenzyme that is found in the mitochondria (the “energy powerhouses”) of all living cells. It is heavily involved in DNA repair and cellular remodeling. It has been known to “turn off” those genes that accelerate degenerative aging and are essential for maintaining neurotransmitter levels for the proper functioning of the brain. It is key in cellular metabolism. The heart, brain and muscle tissue cells contain the highest concentration of NAD+. The more NAD+ present in cells, the more efficiently they function. As we age, our NAD+ levels tend to decline, making us less able to repair cellular damage. We begin to lose energy, appear older and have decreased brain function. 

NAD+ plays a significant role in anti-aging. With NAD+ the molecule works rapidly to repair cells throughout the body and neurons in the brain. It serves as a catalyst in ultimate brain restoration which assists in overcoming depression, anxiety, and common mood disorders. Restoring and supplementing NAD+ in the body may improve physical appearance, health, and quality of life. 

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Sermorelin treatments have proven effective for many patients, and some benefits include but are not limited to: enhanced energy, improved mood, improved sleep, increased bone density, increased mental acuity, reduced feelings of anxiety and depression, weight loss or muscle mass improvement. 

Sermorelin injections can cause some common side effects at the site of injection, like irritation, itching, sensitivity, swelling, pain, and redness. Less common side effects include difficulty in swallowing, dizziness, flushing (redness in face/neck), headache, nausea, rash, sleepiness, taste changes and trouble sitting still. These usually only last a short time and don't require any special action to stop them. If you notice worsening side effects with injection, hold medication and consult your medical provider for further recommendations. Importantly, if you develop signs/symptoms of a severe allergic reaction, such as swelling of the lips/tongue/face or difficulty breathing, please call 911 and seek emergency care immediately. 

Regular B12 injections may:

● Boost energy and reduce fatigue

● Improve focus, memory, and mood

● Support nervous system and brain health

● Aid red blood cell formation and oxygen transport

● Enhance metabolism and mitochondrial function

● Promote better sleep patterns and circadian rhythm

● Support methylation and detoxification processes

● Help reverse deficiency symptoms like numbness or tingling

B12 is generally safe and well-tolerated. Mild, temporary effects may include:

● Redness, swelling, or bruising at injection site

● Increase in fatigue

● Mild headache or dizziness

● Nausea (rare)

● Flushing or warm sensation (transient)

● Rarely numbness, tingling of extremities

 If you notice persistent symptoms or have a history of sensitivity, switch injection sites or reach out to our team.

Supplementation of NAD+ may: 

- Increase energy levels 

- Enhance mood & mental clarity 

- Reverse the visible effects of aging 

- Reduce fatigue 

- Restore muscle function and athletic performance 

- Restore brain chemistry and neurotransmitter function 

- Prevent & correct damage to DNA 

- Regulate inflammation that damages DNA 

- Improve physical appearance, health, and quality of life

How long will it take before I feel the benefits or see results?

The time it takes to feel the benefits or see results from using NAD+ can vary depending on your individual health goals and how your body responds to the supplement. Some people experience an instant energy boost, while others may notice a more gradual improvement in recovery.

The majority of individuals do not encounter any adverse effects from using NAD+.

Should you experience any sensitivity after using the NAD+, consider selecting a different site on your body for the next injection. As with any side effect, if symptoms continue, cease use and get in touch with our team.  Some side effects that can be experienced with NAD+ include headache, flushing, nausea, diarrhea, dizziness, cramping, fatigue, redness or bruising at the injection site. 

How long should you use sermorelin?

Sermorelin therapy is best for three to six months, but can be taken for up to a year. It causes cellular changes in the body, which take time for the body to adjust and fix. While it's safe for most people and long-term use doesn't have serious side effects, you should always follow your doctor's instructions. People with active cancer are not advised to take sermorelin as it may stimulate cancer cell growth.

In order to prevent saturation and desensitization of the growth hormone receptors in the body, it is recommended to use sermorelin on a 5 days on/2 days off schedule. 

Also, a holiday washout period recommended for 2 weeks every 6 months to prevent tolerance and decreased efficacy. 

Where can I inject sermorelin?

Sermorelin can be injected under the skin in different places, such as the lower abdomen, outer thigh, or upper arms. Good procedures should be followed when giving medicine, such as wiping the bottle's cap with antiseptics before inserting a needle.

Does sermorelin affect testosterone?

Sermorelin helps with many bodily functions, such as decreasing body fat, increasing endurance and strength, increasing lean muscle mass, and improving sleep. However, there is no scientific evidence that it increases testosterone levels in men or women.

When should I take sermorelin?

Sermorelin should ideally be taken before bedtime, as this is when the body produces the most growth hormone and repairs tissue. Taking it during the day is also an option, but important to note daytime fatigue can be a side effect, although extremely rare. The dose should be administered by subcutaneous injection and you should rotate injection sites regularly.

How much sermorelin should I inject?

Sermorelin is only available by prescription, and the dosage you need can vary from person to person. Your doctor will tell you the right dose for you. Make sure to follow the prescription closely and do not use more or less than what is prescribed. Altering the doses without your doctor's advice can increase the risk of side effects or lead to sub-therapy, so it's best to stick to what your physician has told you.

Is sermorelin FDA-approved?

Sermorelin, under the trade name Geref, was approved by the US Food and Drug Administration in 1997. In 2008 it was withdrawn due to difficulties with manufacturing, not safety issues. There are currently new drug applications for sermorelin acetate injection.

Can females take sermorelin?

Both males and females can take sermorelin, and it carries out essential functions in both sexes. Common effects include: enhanced energy, improved mood, better sleep, increased bone density, improved mental acuity, reduced anxiety and depression, weight loss or muscle mass improvement. Sermorelin has also been reported to have skin-repair benefits such as skin softening, tightening, less wrinkles and blemish reduction.

Can sermorelin cause blood clots?

Sermorelin, a synthetic human growth releasing hormone, generally does not cause major side effects including blood clots. Common side effects include dizziness, flushing, headaches, sleepiness and injection site reactions.

Is sermorelin prescription only?

Sermorelin is only available with a doctor's prescription and it is illegal to buy or sell it without one. Be careful of products claiming to contain sermorelin found online - they may be fake or include ingredients you don't know about. Get an accurate evaluation and recommendation from your doctor.

Does sermorelin make you tired?

Sermorelin is known to cause more restful sleep which can lead to sleepiness, due to its effect on growth hormone and cortisol levels. Other side effects include injection site reactions, flushing, dizziness, hives and headaches. Sermorelin maintains your circadian rhythm which helps you sleep better, elevates your mood and promotes restful sleep - the best time to take it is at night.

Does sermorelin increase appetite?

Sermorelin has been shown to increase appetite via an increase in ghrelin (hunger hormone) levels. 

What is the shelf life of the B12 product?

● Unopened: Up to 12 months when refrigerated and kept away from light.

● Opened: Use within 3 months and store in the fridge to maintain potency.

Where and how do I inject B12?

● Type: Subcutaneous (SQ) 

● Sites: Upper outer arm, thigh, hip, or abdomen

● Technique: Pinch the skin (for SQ); inject at a 45° angle for SQ. Rotate sites to reduce irritation or scar tissue.

What time of day is best to inject?

Morning is ideal due to its energizing effect. Some also report better mood and focus when injecting before work or workouts.  Although any time of day is possible for injection.  

Will I feel anything after the injection?

Many people report an increase in energy, mental sharpness, or mood elevation within hours to days. Others notice more gradual effects over a few weeks. If you feel unusually tired afterward (rare), it may be part of your body’s detox response—rest and hydrate.  You may also notice a brightness or fluorescent color to your urine while on B12, this is normal and is not concerning.  

How do I eliminate air bubbles from my vial or syringe?

● Tap or flick the vial gently to raise bubbles to the top

● Let the vial sit undisturbed if bubbles persist

● Insert the needle slowly and draw up with care

● Push a bit of air into the vial before drawing to ease pressure and help bubble displacement

What should I do if I inject too much B12?

Injectable B12 is water-soluble—your body will excrete excess via urine. Overdosing is rare and usually not dangerous, but it’s always best to stay within your prescribed dosage. Contact us if symptoms are unusual or persistent.  You may temporarily notice an increase in fatigue for a few days, this should dissipate as levels return to more physiological levels.  

Can I use injectable B12 while pregnant?

Vitamin B12 is critical during pregnancy, but all injectable therapies should be used under direct supervision of your OB provider. Do not start B12 injections without medical clearance during pregnancy or while breastfeeding.

Can I share my B12 injections with someone else?

No. Your injectable B12 is prescribed specifically for your health profile and dosing. Sharing could lead to misuse, complications, or contamination. Encourage your friend to consult a medical provider instead.

How soon will I feel results?

Some feel improvement in energy or cognition within 24–72 hours. If you have a more significant deficiency or methylation issues (e.g., MTHFR gene variants), benefits may become more noticeable over several weeks of regular use.

Can I inject B12 into different areas of my body?

Yes—use any recommended injection sites (abdomen, upper arm, outer thigh, hip). Always rotate sites to reduce risk of irritation. Do not inject into bruised or inflamed tissue.

What if I bruise after an injection?

Apply gentle pressure immediately after injecting. Avoid rubbing the area. Apply ice to reduce bruising. Do not inject near the bruise until it heals completely. If bruising recurs often, check your injection technique with our team.

What if my order arrived and no one was home?

B12 is stable at room temperature for several days. Refrigerate as soon as possible. While refrigeration is ideal, short periods at ambient temperature will not degrade the product.

Will the injection hurt?

Some mild stinging or soreness is possible, especially if the solution is cold. You can let the vial sit at room temperature for 15–30 minutes before use. Use a new, sharp needle and change injection sites regularly to minimize discomfort with each injection.

How do I dispose of needles and vials?

● Use a puncture-proof sharps container

● Do not dispose of needles in household trash

● Bring filled sharps containers to approved disposal sites or use a mail-back program

● Visit SafeNeedleDisposal.org for a drop-off site near you

Can I use injectable B12 if I have cancer?

There is no conclusive evidence that B12 promotes cancer, but high-dose B12 should only be used under medical supervision if you have active or recent cancer. Speak to your oncologist before beginning injectable therapy.  It is generally recommended to avoid injectable B12 with active cancer. 

How do I open the B12 vial?

Remove the central metal tab. Wipe the rubber stopper with an alcohol swab before each use. Keep the vial refrigerated and away from direct sunlight.

How do I get the last of the B12 from the vial?

● Tilt the vial so the fluid collects in one corner

● Insert air into the vial to increase pressure before drawing

● Use a gentle swirl and tap to move liquid toward the syringe entry point

● Invert and draw slowly to reduce air bubbles

What is the shelf life of the NAD+ product?

Once opened, the product is good for 3 months. If unopened, it maintains its quality for 12 months.

How can I easily eliminate air bubbles from my vial?

Gently tap the vial: Hold the vial between your thumb and index finger, and gently tap it with your other hand. This will help the air bubbles rise to the top of the liquid.

Flick the vial: Another option is to flick the vial lightly with your finger. This can also help dislodge any stubborn air bubbles and make them rise to the surface.

Swirl the vial: Gently swirl the vial in a circular motion to encourage the bubbles to rise to the top.

Let the vial sit: If the bubbles are persistent, allow the vial to sit undisturbed for a short period of time. The bubbles should gradually rise to the surface on their own.

Inverting the bottle to draw up the desired amount should also help eliminate any air bubbles in the syringe even if they are present in the bottle.

What should I do if I accidentally take too much?

If you happen to take more than the suggested amount, don’t worry! The NAD+ in your vial is designed with safety in mind, containing levels that your body can handle. However, it’s always best to stick to the recommended dosage for optimal results.

In case you do take extra, keep in mind that your body may not effectively absorb or break down the excess NAD+ supplement. While it’s generally not a cause for concern, it’s always a good idea to consult with a healthcare professional if you have any doubts or experience any unusual symptoms.

Can I take NAD+ while I’m pregnant?

We strongly advise against the use of NAD+ during pregnancy. There is currently no reliable evidence to confirm its safety for pregnant individuals or the developing fetus. The potential risks are unknown, and taking unverified supplements during pregnancy could pose harm. Please consult with your obstetrician or healthcare provider for further guidance before considering any supplements. 

Can I share my NAD+ with a friend?

We strongly advise against sharing your NAD+ with anyone, including friends. Supplements like NAD+ should only be used under the guidance of a healthcare provider, as individual health needs and conditions vary. Sharing supplements could lead to improper use, unexpected side effects, or interactions with medications your friend may be taking. Encourage your friend to consult their healthcare provider before considering NAD+ or any other supplement.

Will I feel anything after administering NAD+?

Most people don’t experience any side effects, and report feeling alert and energized. If you do feel anything unusual, such as a temporary fatigue for a day or 2, which can happen but is rare, stop using and contact our team. 

Can I use my NAD+ injectables on other parts of my body?

Always ensure you’re using your NAD+ injectibles on the recommended areas of your body. These injectables are specifically designed to deliver NAD+ injectables into the subcutaneous layer, just below the skin, where it’s absorbed efficiently and effectively. It’s important to note that NAD+injectables are not intended for intravenous or intramuscular use. If you experience any irritation while using your injectable, try applying it at a different recommended site on your body, or seek medical advice..

I dropped my injectable on the floor. Can I still use it?

If you happen to drop your injectable on the floor, it’s best not to use it, as it may have been contaminated. Just dispose of the dropped micro injectable in the provided sharps bin and grab a fresh one to ensure cleanliness and safety. That said, if a capped syringe is dropped, there should be no need to discard.

How should I dispose of the needles and vials?

Dispose of any used items, such as your empty vial and needles, in the designated sharps bin. When disposing of needles, it’s important to be cautious and ensure that they are not sticking out of the bin. This helps ensure a clean and responsible process.

Where to dispose of the needles?

Use a puncture-proof sharps container to dispose of used needles. 

Alternative option: A thick, hard plastic container with a secure lid (like an empty laundry detergent bottle) can serve as a temporary container.

Once the container is filled, they should dispose of it at an authorized drop-off location or participate in mail-back programs.

Where can I obtain a sharps container?

Obtain proper sharps containers from: